Widowed twice, this mother of eight children moved west by wagon, first to St. Louis and later to Camp Collins, Colorado Territory. At age 65, she opened the first hotel in Fort Collins, feeding and lodging travelers along the Overland Trail and serving as the area’s only midwife. That same year, Stone and her business partner built a three-story grist mill, the town’s tallest building and the second flour mill in northern Colorado. By 1870, at age 68, she had turned to brick making, eventually building the first brick building in town, where she ran a small hotel. She continued in the hotel business until she was 81.